ODM High Quality Nattokinase Powder for Supplements Suppliers, Factory
Product Description
Nattokinase Powder is a powerful supplement known for its many health benefits. Derived from fermented soybeans, this enzyme has been a cornerstone of traditional Japanese medicine for centuries and is revered for its significant impact on cardiovascular health.
Nattokinase Enzymes help maintain healthy blood flow, reduce the risk of blood clots, and promote overall heart function by breaking down fibrin, a protein that can build up and lead to excessive clotting. In addition to its cardiovascular benefits, Nattokinase Enzymes also have significant anti-inflammatory effects that can help relieve pain and swelling throughout the body. This makes Nattokinase Enzymes beneficial for managing conditions associated with chronic inflammation.
Its potential extends to supporting those with hypertension, where it may help improve blood pressure regulation. Additionally, emerging research suggests that Nattokinase Enzymes can enhance cognitive function, potentially supporting mental clarity and cognitive health. With its wide range of benefits, Nattokinase Enzymes is an excellent choice for those seeking to enhance their overall health and support various aspects of wellness.
Nattokinase Powder are natural enzymes that were originally discovered in the traditional Japanese food "Natto". Natto is made from soybeans fermented by Bacillus subtilis. Nattokinase Enzymes are produced during this fermentation process and improve blood fluidity mainly by breaking down fibrin, a protein in blood clots.
Nattokinase Enzymes are widely used to improve cardiovascular health and prevent thrombotic diseases because they promote blood circulation and reduce the formation of blood clots by acting as a blood viscosity reducer and fibrinolytic agent. Nattokinase Enzymes are oligopeptidases composed of 276 amino acid residues with a molecular weight of approximately 30 kDa.
Nattokinase Enzymes can degrade coagulation proteins such as fibrinogen and fibrin into small peptides and hemolysin (FDP), thereby preventing the formation of blood clots. In addition, Nattokinase can reduce plasma low-density lipoprotein (LDL) levels, thereby preventing the development of cardiovascular diseases such as atherosclerosis.
| ITEMS OF ANALYSIS | SPECIFICATION |
| Appearance | White or Light Yellow Powder |
| Odor | Characteristic odors |
| Activity of enzyme | 20,000FU/g |
| Moisture | ≤8.0% |
| Loss on ignition | ≤5.0% |
| Heavy metals | <30.0ppm |
| Pb | <2.0ppm |
| Cd | <0.5ppm |
| Hg | <0.5ppm |
| As | <2.0ppm |
| Total Plate count | <10,000 cfu/g |
| E.coli | None detected in 10g |
| Salmonella | None detected in 10g |
| Yeast and Mould | NMT 100 cfu/g |
Nattokinase Powder reduces blood clots, which are an important defense mechanism of the body formed by a series of chemical reactions between special blood cells (platelets) and proteins (clotting factors) in the blood. Sometimes this process becomes abnormal and an abnormal clot (also called a thrombus) forms in the artery or vein, blocking blood flow to surrounding tissues.
Nattokinase Powder can prevent atherosclerosis, a chronic disease in which arteries harden through the formation of plaques. Major risk factors include dyslipidemia, diabetes, smoking, high blood pressure, and genetic abnormalities. A randomized controlled trial was conducted on two groups (82 patients with hyperlipidemia for 26 weeks), one group was given a lipid-lowering drug: simvastatin (simvastatin 20 mg) and the other group was given Nattokinase Enzymes (daily dose of 6000 FU). Both groups showed a reduction in carotid artery intima-media thickness (CCA-IMT) and carotid plaque size, but the magnitude was more pronounced in the nattokinase group. In addition, lipid parameters such as TG, TC and LDL-C decreased in both groups of rats, but the magnitude was more significant in the simvastatin group, while Nattokinase Enzymes was able to increase HDL-C.
Hypertension is a fundamental public health problem. In addition to coronary heart disease and stroke, complications include heart failure, peripheral vascular disease, renal impairment, retinal hemorrhage and visual impairment.
Globally, hypertension causes approximately 7.5 million deaths each year, accounting for 12.8% of all deaths, and is expected to increase to 1.56 billion by 2025. A randomized, double-blind, placebo-controlled trial (in 86 patients with prehypertension or stage 1 hypertension) showed that oral Nattokinase Enzymes (2,000 FU) for 8 weeks reduced blood pressure values (systolic blood pressure -5.55 mmHg and diastolic blood pressure -2.84 mmHg) compared with placebo.
Dyslipidemia is central to the development and progression of atherosclerosis, which can lie dormant for decades before triggering the first major cardiovascular event. In guidelines around the world, low-density lipoprotein cholesterol (LDL-C) is designated as the primary therapeutic target for patients with dyslipidemia. A randomized, double-blind, placebo-controlled, parallel-group study (6 months in 47 hyperlipidemia patients) was conducted in 3 groups: nattokinase group, nattokinase combined with red yeast rice extract, and placebo. The study found that the effect of the single formula (nattokinase) on lipids was not evident until the 6th month, while the combined formula (nattokinase combined with red yeast rice extract) improved all lipid indices from the 1st month.
Nattokinase Enzymes can also improve nasal polyps. Nasal polyps (NPs) are inflammatory growths of sinus tissue. Although they can be observed in a variety of clinical conditions, including allergies, asthma, infections, fungi, cystic fibrosis, and aspirin sensitivity, NPs associated with chronic sinusitis are the most common.
Depending on the location and size of the polyps, the main symptoms of NPs are nasal congestion, runny nose and nasal reflux, loss or decreased sense of smell, taste changes, and facial pain.
In an in vitro study, Nattokinase Enzymes solution was shown to shrink nasal polyp tissue through its fibrin-degrading properties and also reduce the viscosity of nasal mucus and sputum compared to saline.
Nattokinase Enzymes are widely used as dietary supplements for their cardiovascular benefits. Derived from fermented soybeans, this enzyme plays a vital role in preventing blood clots by breaking down fibrin, a protein that aids in clot formation. It also helps regulate blood pressure and enhances overall circulation. As a result, Nattokinase Enzymes are popular among individuals who want to support heart health, improve blood vessel function, and promote overall health through natural supplements.
In the cosmetics industry, Nattokinase Powder are being explored for their beneficial anti-inflammatory and antioxidant effects. It can be incorporated into skin care products to help reduce redness and swelling, which is particularly useful for sensitive or irritated skin. In addition, by improving blood flow to the skin, Nattokinase supports a more vibrant and healthy complexion. The inclusion of Nattokinase Enzymes in cosmetic formulations reflects the growing trend of using natural ingredients that offer a variety of benefits for skin health and appearance.
Nattokinase Powder are being investigated for their therapeutic potential in the pharmaceutical sector, particularly due to their fibrinolytic properties. They are being studied for their ability to break down fibrin, which could lead to new treatments for conditions such as deep vein thrombosis (DVT) and stroke. Research on nattokinase enzymes is aimed at determining their effectiveness and safety as a natural alternative or supplement to traditional anticoagulant therapy, potentially providing new options for managing thrombosis-related conditions.
Nattokinase Powder are increasingly being included in functional foods, which are foods designed to provide additional health benefits beyond basic nutrition. Nattokinase enzymes' effects in enhancing blood flow and reducing clot formation make them valuable ingredients in products designed to support cardiovascular health. Functional foods such as fortified cereals, beverages, and snacks containing nattokinase cater to consumers seeking to promote heart health and overall well-being through their diets.
Nattokinase Powder is a natural enzyme produced during the fermentation of non-GMO soybeans by the beneficial bacterium Bacillus subtilis natto. It is then carefully isolated and purified to retain optimal enzymatic potency.
Our standard premium technical specification offers a guaranteed high enzymatic potency of 20,000 FU/g (Fibrin Units per gram), ensuring superior effectiveness for dietary supplement manufacturing.
Nattokinase works primarily as a fibrinolytic enzyme that cleaves cross-linked fibrin directly, helps lower blood viscosity, breaks down blood clots, and assists in maintaining balanced blood pressure and arterial flexibility.
Yes, thanks to its notable anti-inflammatory and antioxidant profile, it is incorporated into soothing cosmetic formulas to calm redness, ease tissue swelling, and encourage local skin microcirculation.
To preserve enzyme activity and prevent moisture degradation, Nattokinase powder should be stored in tightly sealed containers in a cool, dry environment away from direct light, excessive heat, and humidity.
Because Nattokinase possesses natural fibrinolytic and clot-dissolving capabilities, individuals already taking prescription anticoagulant or antiplatelet medications should consult a physician before using nattokinase supplements.
