Custom Palmitoyl Pentapeptide-4 powder Suppliers, Factory
Product Description
Product Description
Xi'an Le-Nutra Ingredients Inc is one of the most professional manufacturers and suppliers of palmitoyl pentapeptide-4 powder in China, featured by quality products and low price. Please rest assured to wholesale bulk palmitoyl pentapeptide-4 powder for sale here from our factory. Customized orders are welcome.
Palmitoyl Pentapeptide-4 powder has enjoyed a long-standing reputation in the global skincare industry under the name ‘Pentapeptide-4’. This bioactive peptide, modified with a palmitoyl chain, belongs to the renowned ‘signalling peptide’ family. Its core mechanism lies in mimicking the pro-collagen fragment of Type I collagen. When skin sustains damage or undergoes ageing, it sends a disguised ‘repair signal’ to fibroblasts, prompting the skin to initiate spontaneous synthesis of collagen, elastin, and hyaluronic acid. As a classic anti-ageing star ingredient, it reshapes the extracellular matrix (ECM) from the skin's basal layer, significantly diminishing deep wrinkles and enhancing skin firmness.
Specification
| Product Name | Palmitoyl Pentapeptide-4 powder |
| Other Names | Palmitoyl Pentapeptide-4, Palmitoyl Pentapeptide-4 raw material, Palmitoyl Pentapeptide-4 cosmetic ingredient |
| Appearance | White powder |
| Purity | 99% |
| CAS No. | 214047-00-4 |
| Molecular Formula | C39H75N7O10 |
| Molecular Weight | 802.05 |
| Grade | Cosmetic grade |
| Shelf Life | 24 Months |
| Storage | Cool Dried Storage |
| Packaging | Aluminum Foil Bag / Carton |
Product Characteristics
By incorporating a palmitic acid fatty acid segment, the predominantly hydrophilic peptide structure gains lipophilic properties, thereby enhancing its penetration capacity within the skin's stratum corneum. This facilitates delivery into the dermis and participation in skin metabolic processes.
Palmitoyl Pentapeptide-4 functions as a signalling peptide, regulating normal physiological activities within skin cells even at low concentrations. Compared to certain more irritating traditional anti-ageing ingredients, it demonstrates superior long-term tolerability, making it particularly suitable for daily skincare formulations.
Research indicates this ingredient exhibits correlations with the synthesis and maintenance of Type I, III, and IV collagen, thereby supporting dermal structural integrity and preserving the stability of the dermal-epidermal junction (DEJ).
Palmitoyl Pentapeptide-4 demonstrates robust stability under standard cosmetic processing and storage conditions, exhibiting minimal sensitivity to light exposure and temperature fluctuations. It is also compatible with common formulation ingredients such as hyaluronic acid, polysaccharides, and plant extracts, making it suitable for diverse dosage form designs.
As one of the longer-established functional peptides with relatively comprehensive research data, Palmitoyl Pentapeptide-4 raw material has been widely incorporated into various anti-ageing skincare products. It enjoys high industry acceptance and a well-established market foundation.
Products Efficacy
Palmitoyl Pentapeptide-4 powder is known as the ‘cell signalling messenger’. It mimics signals released by damaged collagen, prompting fibroblasts to synthesise new collagen, elastin, and fibronectin. Clinical data confirms this peptide significantly increases dermal thickness, effectively ‘lifting’ wrinkles from within the skin. It demonstrates exceptional efficacy in reducing crow's feet, forehead lines, and nasolabial folds.
Beyond protein synthesis, this peptide effectively stimulates hyaluronic acid production (a glycosaminoglycan). This not only boosts deep-skin water retention but also restores elasticity and fullness to dehydrated, ageing tissue by enhancing extracellular matrix density, thereby improving facial contour laxity.
Palmitoyl Pentapeptide-4 cosmetic ingredient boosts expression of Type IV collagen, the cornerstone of dermal-epidermal junction (DEJ) stability. By strengthening the epidermal-dermal interface, it prevents sagging while optimising nutrient transport from dermis to epidermis, revitalising the complexion.
This ingredient supports the repair process by engaging with the skin's intrinsic physiological regulatory mechanisms, rather than through irritation or exfoliation. It repairs damaged basement membranes without compromising the barrier function, making it an ideal choice for sensitive skin and post-aesthetic treatment recovery products.
Market Applications
Palmitoyl Pentapeptide-4, a cosmetic ingredient, is frequently employed as a key functional component in anti-ageing serums, touted for its ‘retinol-like efficacy with zero irritation’. Suited for formulations emphasising long-term wearability and high tolerance, it is often utilised to complement traditional anti-ageing ingredients in synergistic formulations.
Ideal for incorporation into day creams and night care products, it leverages the skin's night-time repair window to deeply replenish the collagen matrix. It supports the sustained replenishment of skin structure-related components, addressing daily care needs for dryness, laxity, and similar skin conditions.
Owing to its gentle nature, Palmitoyl Pentapeptide-4 powder is frequently incorporated into eye serums, eye creams and other periocular formulations. It is well-suited for long-term care regimens targeting concerns such as fine lines and laxity.
In certain post-treatment recovery formulations, this ingredient supports the restoration of skin barrier function and structural integrity. It is suitable for daily recovery regimens following phototherapy or other non-invasive aesthetic procedures.
It may be incorporated into neck creams, body lotions, and other products targeting areas prone to laxity. Functioning as a structural stability-supporting additive, it broadens the application scope of anti-ageing skincare.
Market Applications & Trends
By 2026, consumer focus on skin barrier health will peak, with safe and effective signalling peptides like this one replacing traditional irritating anti-wrinkle ingredients on a large scale.
Single-peptide formulations fall out of favour as markets embrace multidimensional anti-ageing matrices combining bulk Palmitoyl Pentapeptide-4 with hexapeptides (anti-expression lines) and copper peptides (repair).
Brands increasingly favour synthetic peptides with high purity and non-animal-derived certification to meet stringent ESG regulatory standards.
Why Choose Le-Nutra's Palmitoyl Pentapeptide-4 powder
Le-Nutra, as a Palmitoyl Pentapeptide-4 manufacturer with years of specialisation in plant extraction and peptide synthesis, not only supplies you with high-purity active ingredients but is also committed to creating profound commercial value through our end-to-end service.
Leveraging our factory-direct model of ‘Research Centre to Warehouse’, we eliminate intermediary mark-ups entirely, ensuring you secure premium-quality raw materials at highly competitive source pricing. Our specialised application laboratories serve not only as production hubs but as your technical support arm. We assist in optimising formulation architecture, provide comprehensive stability testing data and ingredient compatibility recommendations, ensuring optimal ingredient efficacy within your finished products. We support bespoke packaging from 1g R&D samples to 10kg industrial bulk orders, delivering unparalleled responsiveness to help your brand seize competitive advantage in fiercely contested markets.
Our Package
Inner by food grade plastic bag; Outside with kraft paper bag; Available in 15kg/25kg/bag, also accept customized quantity.
Frequently Asked Questions
Yes. It is non-acidic and will not cause irritation due to pH fluctuations. In fact, combining peptides with retinol (a new trend following the “morning C, evening A” routine – peptide stabilisation) effectively alleviates the dryness associated with retinol.
Palmitoyl Pentapeptide-4 is a cosmetic signalling peptide ingredient. Its INCI name is Palmitoyl Pentapeptide-4, and it is also commonly referred to as Pentapeptide or Matrixyl® (trademark). This ingredient modifies the pentapeptide structure with fatty acids (palmitoyl) to enhance its stability and formulation compatibility in skincare products. It is widely used in anti-ageing skincare formulations.
Yes. Palmitoyl Pentapeptide-4 is frequently incorporated into multi-peptide complexes, such as formulations combining Acetyl Hexapeptide-8, Acetyl Octapeptide-3, and Palmitoyl Tetrapeptide derivatives, to construct layered peptide structures. This combination approach is highly prevalent within the contemporary anti-ageing skincare market.
Based on application experience, this ingredient demonstrates good formulation compatibility and is frequently used in products emphasising gentle care concepts. However, prior to formal commercialisation, brands are still advised to conduct necessary safety assessments and skin tests according to their target demographic.
It is recommended to store the product in a cool, dark, dry environment under sealed conditions. Unopened, it generally exhibits good stability; once opened, it should be used promptly and avoided frequent exposure to high temperatures or humid conditions.
As a raw material supplier, we provide stable bulk supply of Palmitoyl Pentapeptide-4 and accommodate custom requirements for varying purities, specifications, and packaging formats. We also furnish technical documentation and application references to support product development and marketing initiatives.
