What ingredient categories does Le-Nutra manufacture?

Le-Nutra manufactures five ingredient families: vegetal proteins (pea, rice, soy isolate, pumpkin seed), hydrolyzed proteins and peptides (wheat, soy, corn, pea, fish collagen), standardized herbal extracts (saffron, lemon balm, chamomile, pomegranate peel), cosmetic and personal care actives (GHK-Cu, ectoine, tranexamic acid, allantoin, D-panthenol) and dietary supplement ingredients.

Which quality documents are available for supplier qualification?

Each product can be supplied with a batch Certificate of Analysis (COA), Safety Data Sheet (SDS/MSDS) and specification sheet. Company certificates are displayed on our website, and product-specific statements can be requested where applicable.

What is Le-Nutra's production capacity?

Our 60,000 square meter production base operates six multifunctional production lines equipped with different types of extraction tanks, with an annual output of about 3,000 tons.

Can specifications be customized for my formulation?

Depending on the product, parameters such as purity or marker-compound content, extract ratio, mesh size, solubility and peptide molecular-weight range can be discussed with our R&D team to match your application.

Which markets does Le-Nutra export to?

Le-Nutra exports natural ingredients to more than 40 countries across North America, Europe, the Middle East, Asia-Pacific and South America, supported by English-language documentation and our global service team.

How can I get the complete Le-Nutra product list?

Use the Request a Catalog page to receive our full ingredient catalog, including categories, typical specifications and available documentation.

Custom Apium Graveolens Celery Seed Extract Manufacturers & Factory

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Phytochemical Standardization

Engineering Apium Graveolens: Botanical Identity & Marker Optimization

Apium graveolens (Celery Seed) represents a multi-functional phyto-matrix containing bioactive phthalides, coumarins, and flavonoids that require high-precision separation to ensure active recovery.

Phthalide Fractions (NBP & Sedanenolide)

Custom extraction controls volatile 3-n-butylphthalide (NBP) and sedanenolide levels, proven in clinical literature to modulate smooth muscle relaxation, microvascular regulation, and xanthine oxidase inhibition for uric acid metabolic pathways.

Flavonoid Profiling (HPLC-Verified Apigenin)

Standardization to pure Apigenin and luteolin derivatives enables neuroprotective, anti-inflammatory, and GABAergic modulation. Controlled crystallization prevents solvent residue issues commonly detected in lower-tier botanical operations.

Supercritical CO₂ Fluid Extraction (SFE)

Thermally sensitive lipophilic fractions are isolated via subcritical and supercritical carbon dioxide extraction under 32–45°C processing thresholds, preserving fragile terpenoids while ensuring zero chemical solvent retention.

Global Market Economics

Global Procurement Demand & Market Trajectory (2025–2032)

The market for Apium graveolens extract is evolving beyond conventional joint health supplements toward targeted pharmaceutical intermediates, hyperuricemia therapeutics, and clinical cosmetics.

Metabolic & Hyperuricemia Solutions

Surging global rates of hyperuricemia and gout have sparked massive procurement demands among dietary supplement formulators. Celery seed's natural dual-action—uricosuric clearance acceleration and xanthine oxidase suppression—positions it as an indispensable non-synthetic active.

Anti-Hypertensive Phytotherapy

NBP fractions are intensively investigated and formulated for systemic arterial dilation and vascular resistance reduction. Contract manufacturers across North America and Europe are systematically replacing unstandardized bulk powders with HPLC-verified NBP extracts.

Cosmeceutical Microcirculation

In skin and scalp barrier management, lipophilic celery seed extracts act as micro-circulation accelerators and anti-inflammatory soothing agents. Formulators rely on standardized, low-odor, color-clarified grades for clean, non-staining topicals.

3,000 t

Annual Group Capacity

60,000 m²

cGMP Facility Footprint

6 Lines

Multifunctional Extraction

40+

Export Nations Served

Engineering Matrix

B2B Product Grades & Tailored Specifications

Our plant controls extraction solvents, separation chromatography, and microencapsulation to deliver tailored physical-chemical parameters matching your exact dosage requirements.

Standardized Grade	Assay Marker / Ratio	Processing Route	Solubility Profile	Target Applications
HPLC Grade Apigenin Focus	Apigenin ≥ 1.0% to 10.0%	Hydroethanolic / Resin Desorption	Partially soluble; dispersible in water	Capsules, Solid Tablets, Sleep Aids
Volatile Phthalide Complex (NBP)	Total Phthalides ≥ 5.0% - 20.0%	Supercritical CO₂ Fluid Extraction	Lipophilic; oil-miscible	Softgels, Liquid Suspensions, Cardio Actives
Water-Soluble Instant Powder	Ratio 10:1 / 20:1 / 30:1	Aqueous Countercurrent Extraction	100% Clarified Instant Solution	Functional Ready-to-Drink (RTD), Stickpacks
Microencapsulated Cold-Water Granule	NBP 2.5% Beadlets	Fluidized-Bed Coating Matrix	Cold-water dispersible; Odor masked	Effervescent Tablets, Dry Premixes
Ultra-Purified Phyto-Cosmetic Grade	Decolorized / Low-Terpene	Molecular Distillation Fractional Cut	Cosmetic Ester & Ethanol Soluble	Scalp Tonics, Soothing Serums, Creams

Integrity & Verification

Global Compliance, Analytical Testing & Localized Support

Reliable supplier qualification depends on transparent, repeatable data. Xi'an Le-Nutra integrates full-suite verification across raw material intake, processing, and customs clearance.

Rigorous Contaminant Controls

Every commercial production batch undergoes mandatory screening via ICP-MS for Heavy Metals (Pb, As, Cd, Hg conforming to USP <232>/<233> and EP 2.8.13). Multi-residue pesticide screens cover over 400 compounds via GC-MS/MS and LC-MS/MS.

Full Dossier & Traceability Support

Shipments are accompanied by English Batch Certificates of Analysis (COA), Safety Data Sheets (SDS), Non-GMO Declarations, Allergen Certificates, and BSE/TSE statements, ensuring straightforward regulatory filing across FDA NDIs, EU Novel Food, and FSANZ frameworks.

Custom Warehousing & Logistics

Strategically timed container shipments and air freight logistics operate alongside regional bonded warehouse staging points, mitigating inventory stockouts and preserving raw material potency during intercontinental shipping.

Innovation Horizon

Technological Roadmap & Next-Gen Bioprocessing

Our Xi'an research center continues to optimize phytochemical yields and functional bioavailability through continuous R&D improvements.

Phase I: Nano-Liposomal Encapsulation

Targeted stabilization of fragile phthalide fractions via food-grade phospholipid liposomal complexes to multiply gastrointestinal stability and enhance cellular absorption kinetics across intestinal membranes.

Phase II: Continuous Enzymatic Pre-Digestion

Integrating proprietary enzymatic wall-breaking cascades directly prior to countercurrent extraction steps, freeing cellularly bound apigenin glycosides while cutting extraction thermal exposure by 40%.

Phase III: Green Circular Biorefinery

Transforming post-extraction celery seed residues into upcycled micronized dietary fibers and low-molecular vegetable proteins, achieving a zero-waste industrial standard aligned with international EcoVadis CSR metrics.

Procurement Inquiries

Apium Graveolens Sourcing & Manufacturing FAQ

Direct technical clarity for supply chain managers, QA analysts, and master formulators.

What are the key chemical marker compounds utilized to evaluate Apium Graveolens Celery Seed Extract quality?

Commercial potency is determined predominantly by HPLC quantification of phthalides—particularly 3-n-butylphthalide (NBP) and sedanenolide—alongside the key flavonoid Apigenin. Lower-grade powders typically state extract ratios without verified chromatographic identification. At Xi'an Le-Nutra, every production batch is released against reference standards to ensure batch-to-batch bioequivalence.

How does your factory overcome the intense herbal odor and volatile flavor profile of celery seed for beverage formulations?

We provide targeted, low-odor, microencapsulated grades and selective chromatographic fractions. By isolating active flavonoids from strong-smelling terpenoid oils or applying cyclodextrin inclusion complexes, our R&D group ensures active solubility and functional stability without overpowering sensory notes in drinks or chewables.

What minimum order quantities (MOQ) and packaging formats apply for custom OEM/ODM production runs?

Standard inventory items have a baseline MOQ of 1 kg to 25 kg fiber drums lined with food-grade double polyethylene bags. Tailored specifications—including custom particle sizing, unique solvent blends, or specialized marker ratios—carry an MOQ of 100 kg to 500 kg, supported by small-scale pilot batches for initial verification.

Are your celery seed extracts compliant with international ethylene oxide (ETO) and irradiation guidelines?

Yes. All manufactured botanical batches are strictly non-irradiated and 100% free of Ethylene Oxide (ETO) sterilants. Microbial thresholds (Total Plate Count < 1,000 CFU/g, Yeast & Mold < 100 CFU/g, Negative Salmonella/E. coli) are achieved through controlled closed-loop steam processing and cGMP clean-room drying.

Can Xi'an Le-Nutra furnish analytical validation methods alongside standard COAs for in-house laboratory testing?

We provide full analytical dossiers upon request, complete with HPLC conditions, column parameters, mobile phase ratios, flow rates, and detector wavelengths. This ensures seamless method transfers and fast qualification inside client laboratories.